- September 25 1066: the Battle of Stamford Bridge takes place between Norwegian forces led by Haraldr Harðráði and Ænglisc forces led by Harold II of Ængland; the battle ends in an Ænglisc victory and the deaths of Harðráði and his other commanders
- October 14 1066: the Battle of Hastings takes place between Ænglisc forces led by Harold II of Ængland and Norman forces led by William II, Duke of Normandy; the battle ends when the Normans retreat under the misbelief that William II was killed
- 1532: Niccolò Machiavelli's Il Principe is published
- June 26 363: Julian the Apostate is mortally wounded during the Battle of Samarra, possibly by one of his own soldiers
- c. 1248: the Aztecs arrive in the Valley of México
- March 13 1428: the Ēxcān Tlahtōlōyān (Aztec Triple Alliance) is founded
- August 13 1521: Tenōchtitlān is conquered by Spanish conquistadors, bringing the Ēxcān Tlahtōlōyān (Aztec Triple Alliance) to an end; though the Aztecs are defeated, they are not wiped out
- February 28 1525: Cesare Borgia forms the Méxican Empire as a puppet state under his control
- c. 1627: the aurochs becomes extinct
- 1768: the Steller's sea cow becomes extinct
- c. 1800: the bluebuck becomes extinct
- May 1821: Napoléon Bonaparte dies of stomach cancer, though some suggest that he was actually poisoned
- May 30 1848: the Treaty of Seville is signed and Spain recognizes Ānāhuac as an independent country
- 1865: Charles Darwin predicts that the Falkland fox is doomed to extinction
- 1870: the last Atlas bear is killed by hunters
- 1880: the Falkland fox is hunted to extinction
- November 15 1904: Al Swearengen is found dead of a massive head wound
- 1906: the mourning caracara is wiped out by this year
- 1909: the last known tarpan dies in captivity
- February 5 1917: the Political Constitution of Ānāhuac is ratified, bringing the Aztec Empire to its current system of government
- 1936: the last known thylacine dies in captivity
- 1971: the Abingdon Island tortoise Lonesome George is found, proving that the species is not yet extinct
- January 2000: the Pyrenean ibex becomes extinct
- 2003: the Pyrnean ibex is briefly brought out of extinction through cloning
- 2011: the western black rhinoceros is declared extinct
- 2012: the Abingdon Island tortoise becomes extinct when Lonesome George dies
- 2016: Arapaima gigas is hunted to extinction